microarrays of complementary dna (Operon Biotech)
Structured Review

Microarrays Of Complementary Dna, supplied by Operon Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/microarrays of complementary dna/product/Operon Biotech
Average 90 stars, based on 1 article reviews
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1) Product Images from "Induction of DNA strand breaks is critical to predict the cytotoxicity of gemtuzumab ozogamicin against leukemic cells"
Article Title: Induction of DNA strand breaks is critical to predict the cytotoxicity of gemtuzumab ozogamicin against leukemic cells
Journal: Cancer Science
doi: 10.1111/j.1349-7006.2012.02343.x
Figure Legend Snippet: Protein expression levels of DNA repair proteins. Genes found to be altered in two gemtuzumab ozogamicin (GO)‐resistant subclones (HL/GO, HL/GO‐CSA) were evaluated for their protein expression levels by Western blotting.
Techniques Used: Expressing, Western Blot
Figure Legend Snippet: Relationship between gemtuzumab ozogamicin (GO)‐associated parameters and GO sensitivity. (A) Tail moment values (number of DNA strand breaks) and IC 50 values were plotted within the same cell line (HL‐60, HL/GO, HL/GO‐CSA, HL/Ara‐CDNR, K562). The IC 50 values were determined using the XTT assay. Tail moment values were determined by the Comet assay after cells had been treated with 10 μg/mL GO for 6 h. The values are the means of triplicate determinations. (B–D) Similarly, the correlation between the IC 50 values and each of the factors (CD33 positivity, P‐glycoprotein [P‐gp] expression, and multridrug resistance protein‐1 [MRP1] mRNA) were evaluated. (E) Comparison was made between the CD33‐positive/P‐gp‐negative/MRP1‐negative cell lines (HL‐60, K562) and the others (HL/GO, HL/GO‐CSA, HL/ara‐CDNR). Bars represent the means.
Techniques Used: XTT Assay, Single Cell Gel Electrophoresis, Expressing, Comparison